Antimalarial Products

Amatem Softgel 20/120 mg

COMPOSITION: Each Soft Gelatin Capsule contains:

```
Artemether Ph. Int.		20 mg
```
```
Lumefantrine Ph. Int		120 mg
```
```
Excipients 			q.s.
```

PHARMACOLOGY

Artemether and Lumefantrine is a fixed dose artemisinin-based combination therapy (ACT) combining artemether, an artemisinin derivative and lumefantrine, a synthetic antimalarial drug.

INDICATIONS

For the treatment of most forms and resistant types of malaria.

CONTRAINDICATIONS

Hypersensitivity to any of the ingredients
Patients who are taking any drug that is metabolized by the cytochrome enzyme CYP2D6 (e.g. Flecainide, metoprolol, imipramine, amitriptyline, clomipramine).

SPECIAL PRECAUTION

It must not be used in first Trimester of Pregnancy

DOSAGE AND ADMINISTRATION

STORAGE OR HANDLING RECOMMENDATION

Store below 25^oC in a cool and dry place.

PRESENTATION

Amatem Softgel is available in blister packs of 12, 18 & 24 Soft Gelatin Capsules.